Tubular Adenomas and Testis-Like Ovaries of Aged Rats Tubules of the

The material presented here is a result of histological examination of the ovaries of 34 rats from the Wistar series, which were 900 days of age or older. Of this group, 20 were 900 days or slightly older, 10 were 1,000 days or slightly older, and 4 were 1,100 days or more old. For comparison, tissues of t5 female rats of this series ranging between 600 and 900 days, were examined. The animals were killed and autopsied by the staff of the Wistar Institute. In most instances the ovaries were removed with the ovarian capsules and adjacent tubes, fixed in Bouin's fluid, and shipped in 70 per cent alcohol. Both ovaries were imbedded together and cut at 8 /~ in this laboratory. Usually 2 slides, each with 10 to 16 sections, were saved from the middle of the ovary. One slide was stained with Harris hematoxylin and eosin, the other with Masson's trichrome stain. Subsequently other staining methods were used for special purposes.